柞蚕丝素肽的抗氧化及美白功效评价

doi:10.3969/j.issn.2097-2806.2023.08.005

Abstract

Abstract:

Study on antioxidant and whitening efficacy of tussah fibroin peptides was conducted. The results show that the IC₅₀ of DPPH free radical scavenging rate of NO.1 （molecular weight 2 000-5 000 Da） and NO.2 （molecular weight<2 000 Da） samples are 1.41 and 3.84 mg/mL, respectively, and the IC₅₀ of hydroxyl free radical scavenging rate are 0.085 and 0.091 mg/mL, respectively. The total reducing power level increases with the sample dosage. The addition of tussah fibroin peptides have a protective effect on the UV-damaged mouse fibroblasts through increasing the activity of SOD and the content of GSH, and decreasing the content of MDA. In the evaluation of whitening efficacy, the IC₅₀ of No.1 and No.2 samples of tyrosinase inhibition effect rate are 3.65 and 5.84 mg/mL, respectively, which can inhibit melanin synthesis and tyrosinase activity in mouse melanoma cells. In conclusion, tussah silk fibroin peptides have antioxidant and whitening activity, and the NO.1 sample with larger molecular weight is better than the NO.2 sample with smaller molecular weight.

Key words: tussah fibroin peptides, anti-oxidation, resistance to UV oxidative damage

CLC Number:

TQ658

Li Xuejun,Mi Rui,Wang Linmei,Li Yajie,Chen Xue,Du Xingfan. Evaluation of anti-oxidation and whitening efficacy of silk fibroin peptides from tussah Antherae pernyi[J].China Surfactant Detergent & Cosmetics, 2023, 53(8): 891-898.

Figures/Tables 13

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References 26

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检测项目	柞蚕丝素肽1号含量/ （g/100 g）	柞蚕丝素肽2号含量/ （g/100 g）	检测项目	柞蚕丝素肽1号含量/ （g/100 g）	柞蚕丝素肽2号含量/ （g/100 g）
组氨酸	1.33±0.04	1.26±0.11	赖氨酸	0.13±0.01	0.15±0.02
酪氨酸	10.27±0.13	8.97±0.72	丝氨酸	9.20±0.89	9.31±0.92
异亮氨酸	0.47±0.01	0.40±0.08	谷氨酸	1.51±0.32	1.45±0.21
缬氨酸	1.02±0.02	0.85±0.18	甘氨酸	19.53±0.23	18.39±0.64
丙氨酸	39.53±2.02	37.62±1.82	蛋氨酸	0.02±0.01	0.02±0.01
脯氨酸	0.56±0.06	0.54±0.08	亮氨酸	0.54±0.01	0.46±0.03
精氨酸	4.97±0.12	4.63±0.08	苯丙氨酸	0.57±0.02	0.50±0.05
天门冬氨酸	5.16±0.45	5.82±0.52	苏氨酸	0.45±0.02	0.46±0.05

Evaluation of anti-oxidation and whitening efficacy of silk fibroin peptides from tussah Antherae pernyi

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