Abstract:

Combined with objective test data and subjective evaluation method, an 8-week trial was conducted to evaluate the anti-aging efficacy of the Dead Sea water emulsion. Thirty eligible subjects （27-57 years old, female） were selected for this randomized double-blind controlled experiment. 3D images of wrinkles, stratum corneum moisture content, transepidermal water loss and skin elasticity on both cheeks were collected by researchers at 2 weeks, 4 weeks and 8 weeks after using the Dead Sea water emulsion. Subjects were also asked to make a self-assessment of their skin condition at each period. The comprehensive evaluation results show that, all skin indexes of the subjects are gradually improved as the trial duration grows. The 8-week data of facial skin condition are significantly improved after using the Dead Sea water emulsion （P<0.05）. The stratum corneum moisture content is increased by 17.77%; the transepidermal water loss is decreased by 11.29%; the skin elasticity is increased by 17.62%; the depth of nasolabial folds is decreased by 18.23%; the wrinkles of canthus are decreased by 16.71%. The results of all indexes are better than the blank control group. In addition, the self-rating of subjects is also gradually increased in each period. In conclusion, the Dead Sea water applied in emulsion has obviously improved the anti-aging efficacy.

Key words: Dead Sea water, anti-aging, clinical efficacy