双光子成像技术在痤疮丙酸杆菌引起痤疮表皮炎症中的应用

doi:10.3969/j.issn.1001-1803.2020.10.009

Abstract

Abstract:

Changes of epidermal inflammation caused by Propionibacterium acnes （P.acnes） were detected by Two-Photon Excitation Fluorescence （TPEF） imaging technology and other methods. P.acnes in the logarithmic growth phase were injected into the ears of mice, and the changes in epidermal thickness, stratum granulosum, stratum spinosum and stratum basale cells were studied by TPEF imaging technology. Thickness of ear and epidermis were detected by ear thickness measurement and HE staining method. TPEF imaging technology found that the epidermis thickness was increased significantly, the molecules in granular cells were rearranged, and the morphology of stratum spinosum and stratum basale cells was changed after P.acnes infection. Ear thickness measurement and HE staining revealed that the ear and epidermis infected by P.acnes became thicker.

Key words: two-photon imaging technology, Propionibacterium acnes, acne, epidermis, inflammation

CLC Number:

TQ658

HE Gai-ying,TANG Jing-hui,SUN Ya-nan,MA Shu-hua,YANG Wei-feng,WANG Yi. Application of two-photon imaging technology in epidermal inflammation of acnes caused by Propionibacterium acnes[J].China Surfactant Detergent & Cosmetics, 2020, 50(10): 704-710.

Figures/Tables 4

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References 24

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Application of two-photon imaging technology in epidermal inflammation of acnes caused by Propionibacterium acnes

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