中药生发液对小鼠脱发的治疗作用研究

doi:10.3969/j.issn.1001-1803.2019.04.008

Abstract

Abstract:

The therapeutic effect of traditional Chinese medicine hair restorer on hair loss in mice was studied by applying the hair restorer to the hair removal area on the back mice. The effect of hair restorer on hair regeneration rate was evaluated by measuring the newborn hair length on mice. The effect of hair restorer on the morphology of hair follicles and the terminal/vellus hair ratio was evaluated by observing the skin HE staining section. The effect of hair restorer on collagen fiber arrangement was evaluated by observing the skin Masson staining section. The effect of hair restorer on the expression of lactate dehydrogenase（Ldha）was detected by Western Blot. The results show that compared with the control group, the hair regeneration rate is accelerated, the number of hair follicles increases, the terminal/vellus hair ratio increases, collagen fibers arrange more closely and orderly, and the expression of Ldha is up-regulated in the treatment group, which indicate that the traditional Chinese medicine hair restorer has an efficacy of promoting hair growth.

Key words: hair loss, traditional Chinese medicine hair restorer, hair follicle, terminal/vellus hair ratio, lactate dehydrogenase

CLC Number:

TQ658.3

LUO An-ling,CHEN Xin-xin,DING Yun-wen,REYISHA Wu-fuer,ZHENG You-li,CONG Feng-song. Study on therapeutic effect of traditional Chinese medicine hair restorer on hair loss in mice[J].China Surfactant Detergent & Cosmetics, 2019, 49(4): 244-247.

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Study on therapeutic effect of traditional Chinese medicine hair restorer on hair loss in mice

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