Abstract: Schizophyllan polysaccharide phosphorylated derivative was prepared from schizophyllan polysaccharide by modification with sodium tripolyphosphate and sodium trimetaphosphate.The effects of mass ratio of reactants, reaction temperature and reaction time on the degree of substitution were examined by single factor experiments.Experimental results show that the better conditions for the preparation are:mass ratio,m(sodium tripolyphosphate + sodium trimetaphosphate,with equal molar blend)∶m(schizophyllan polysaccharide) = 2∶1;reaction temperature,60 ℃;and reaction time,3 h.Under these conditions,the degree of substitution of phosphorylation achieves 0.052.The solubility,antioxidantion activity and moisturizing capacity of schizophyllan polysaccharide before and after phosphorylation were studied.Results show that the solubility and moisturizing capacity of schizophyllan polysaccharide are greatly improved by phosphorylation modification.The phosphorylation modification displays little effectiveness on improving antioxidation activity of the schizophyllan polysaccharide.

Key words: cosmetic additives, schizophyllan polysaccharide, phosphorylated derivative, preparation, moisturizing