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China Surfactant Detergent & Cosmetics ›› 2017, Vol. 47 ›› Issue (4): 207-211.doi: 10.13218/j.cnki.csdc.2017.04.006

• Development and applicatio • Previous Articles     Next Articles

Study on cosmetological efficacy of glacier water and Meconopsis quintuplinervia extract

CHEN Di1, ZHANG Zhang2, JIANG Yao-quan2, FANG Zhao-hua2, CONG Feng-song1   

  1. 1.School of Life Sciences and Biotechnology,Shanghai Jiao Tong University,Shanghai 200240,China;
    2.Jala Corporation,Shanghai 200040,China
  • Received:2016-11-26 Published:2019-03-20

Abstract: The effect of glacier water and Meconopsis quintuplinervia extract on human dermal fibroblast-adult (HDF-a) was studied respectively and collaboratively.Effect of glacier water and Meconopsis quintuplinervia extract on cell proliferation activity of HDF-a was evaluated by MTT assay and on level of cellular ATP (adenosine triphosphate) with an ATP Assay Kit.Effect of glacier water and Meconopsis quintuplinervia extract on content of hyaluronic acid in extracellular matrix (ECM) of HDF-a was evaluated by Enzyme-linked immunosorbent assay (ELISA) and their effect on expression of collagenⅠand elastin in ECM was detected by Western Blot.The results show that,as comparing with the control group,glacier water can promote the proliferation activity and energy metabolism level of HDF-a as well as enhancing cellular content of hyaluronic acid compared with the control group.Glacier water also displays a capacity of enhancing the expression of elastin.All of the above-mentioned differences are statistically significant.The effect of Meconopsis quintuplinervia extract with respect to the above-mentioned aspects is more obvious than that of glacier water,and the extract shows an ability of promoting the expression of collagenⅠ.When glacier water and Meconopsis quintuplinervia extract are used collaboratively,their efficacy on HDF-a is much more obvious.

Key words: cosmetic additive, glacier water, Meconopsis quintuplinervia extract, HDF-a, anti-sanility, moisturizing

CLC Number: 

  • TQ658