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China Surfactant Detergent & Cosmetics ›› 2016, Vol. 46 ›› Issue (2): 114-117.doi: 10.13218/j.cnki.csdc.2016.02.012

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Progress in research work with respect to in vitro evaluation method on cellular level for efficacy of anti-senility cosmetics

GUO Song-he1,2,GAO He-yi1,ZENG Sa1,ZHANG Ge2   

  1. 1.Ridgepeole & Upright Biotechnology Co.,Ltd.,Guangzhou,Guangdong 510800,China;
    2.School of Pharmaceutical Sciences,Sun Yat-sen University,Guangzhou,Guangdong 510006,China
  • Online:2016-02-22 Published:2016-02-22

Abstract: From three aspects for in vitro evaluation method on cellular level for efficacy of anti-senility cosmetics,i.e.the keratinocytes model,the fibroblast model and the three-dimensional skin model were summarized.The evaluation method is mainly based on the cytological observation and the detection of molecular biological indicators in the cell model of keratinocytes,fibroblast and three-dimensional skin.The application of these techniques has a wide range value for the development and evaluation of skin anti-senility products.

Key words: anti-senility cosmetics, cell model, efficacy evaluation

CLC Number: 

  • TQ658