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China Surfactant Detergent & Cosmetics ›› 2014, Vol. 44 ›› Issue (4): 218-221.doi: 10.13218/j.cnki.csdc.2014.04.049

• Development and application • Previous Articles     Next Articles

Inhibitory effect of taxifolin in Larix olgensis on tyrosinase

FU Jing-hui, CHAI Jing, HAN Jia-tong, LIU Wen-cong   

  1. College of Chinese Medicinal Materials,Jilin Agricultural University,Changchun,Jilin 130118,China
  • Received:2013-10-08 Online:2014-04-22 Published:2019-04-09

Abstract: Taking L-DOPA as substrate,arbutin and BHT as positive controls,the inhibitory effect on tyrosinase of the taxifolin in Larix olgensis was studied and compared with that in Larix gmelini.Results showed that,when the mass concentration of taxifolin is 0.001-0.01 g·L-1,the inhibitory effect of taxifolin in Larix olgensis is higher than that in Larix gmelini on tyrosinase.For Larix olgensis,under low mass concentration range condition,the higher purity of taxifolin,the stronger inhibitory effect on tyrosinase;while under high mass concentration range condition,the higher purity of taxifolin,the weaker inhibitory effect on tyrosinase.Taxifolin in Larix olgensis shows competitive inhibition mechanism for tyrosinase with an inhibition constant KI of 0.017.

Key words: cosmetics, taxifolin, tyrosinase, Larix olgensis

CLC Number: 

  • TQ658