微波辅助法合成季鏻盐

doi:10.13218/j.cnki.csdc.2014.01.004

Abstract

Abstract: Seven kinds of quaternary phosphonium salt were synthesized with halogenated hydrocarbons and triphenylphosphine as starting materials under assistance of microwave irradiation.Effects of reaction temperature,time,kind of solvent,solvent dosage and the molar ratio were studied,and the optimal conditions of the reaction were determined as:adopting DMF,acetonitrile or toluene as the solvent;reaction time,20 min;reaction temperature,120 ℃;molar ratio of triphenylphosphine and halogenated hydrocarbon,1.1∶1;concentration (measured by moles of triphenylphosphine),2.86 mol·L^-1.Under the above mentioned conditions,yield of benzyltriphenylphosphonium bromide product can achieve 93.5%;while yield of other kinds of the quaternary phosphonium salt are also satisfactory.The products were characterized by ¹HNMR and melting point.Under optimal conditions,the time needed for completion of the reaction is no more than 2.8% of that of conventional heating methods.

Key words: quaternary phosphonium salt, triphenylphosphine, halogenated hydrocarbon, microwave irradiation

CLC Number:

TQ423.12

YIN Xiao-gang, ZHAO Zheng-rong, XIAO Wei-jun, CHEN Zhuo, YU Jie. Synthesis of quaternary phosphonium salts under assistance of microwave irradiation[J].China Surfactant Detergent & Cosmetics, 2014, 44(1): 15-18.

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Synthesis of quaternary phosphonium salts under assistance of microwave irradiation

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