皮肤模型在化妆品功效评价中的应用研究进展

doi:10.13218/j.cnki.csdc.2017.04.010

Abstract

Abstract: Three-dimensional reconstructed human-skin models and current status with respect to research work for application of three-dimensional reconstructed human-skin models in the fields of depigmentation and sunscreen,skin barrier function,moisturizing and anti-sanility,sensitiveness releasing and renewal as well as protection against air pollution were summarized.The advantages and disadvantages of the human-skin models used currently were discussed with comments and suggestions for its future development.

Key words: cosmetics, three-dimensional reconstructed human-skin models, efficacy, in vitro assay, animal alternative methods

CLC Number:

TQ658

KONG Xue, ZHAO Hua, TANG Ying. Progress in field of research work for application of human-skin models in efficacy evaluation of cosmetics[J].China Surfactant Detergent & Cosmetics, 2017, 47(4): 228-231.

References

[1] 国家食品药品监督管理总局.食品药品监管总局公开征求《化妆品监督管理条例(征求意见稿)》意见[EB/OL].(2014-11-08) [2016-10-17].http://www.sda.gov.cn/WS01/CL0781/108920.html.
[2] 国家食品药品监督管理总局.化妆品安全技术规范[S].北京:中国标准出版社,2015.
[3] Zuang V,Tuomainen A M,Amcoff P,et al.EURL ECVAM progress report on the development,validation and regulatory acceptance of alternative methods [M].Luxembourg:Publications Office of the European Union,2013.
[4] 程树军,步犁,潘芳.基于黑色素形成机制的美白化妆品功效体外检测方法[J].中国卫生检验杂志,2012(3):665-668.
[5] Son K H,Heo M Y,Son K H,et al.The evaluation of depigmenting efficacy in the skin for the development of new whitening agents in Korea [J].International Journal of Cosmetic Science,2013,35(1):9-18.
[6] Régnier M,Duval C,Galey J B,et al.Keratinocyte-melanocyte co-cultures and pigmented reconstructed human epidermis:models to study modulation of melanogenesis [J].Cellular & Molecular Biology,1999,45(7):969-980.
[7] Sugimoto K,Nishimura T,Nomura K,et al.Inhibitory effects of alpha-arbutin on melanin synthesis in cultured human melanoma cells and a three-dimensional human skin model [J].Biological & Pharmaceutical Bulletin,2004,27(4):510-514.
[8] Gele M V,Speeckaert R,Vanhoecke B,et al.Development of a 3D pigmented skin model to evaluate RNAi-induced depigmentation [J].Experimental Dermatology,2011,20(9):773-775.
[9] Duval C,Schmidt R,Regnier M,et al.The use of reconstructed human skin to evaluate UV-induced modifications and sunscreen efficacy [J].Experimental Dermatology,2003,12(S2):64-70.
[10] 陈旭,甄雅.广谱防晒剂可有效防止UVA在体外重建皮肤及人体皮肤中诱导的基因表达[J].中华皮肤科杂志,2011,44(10):759-760.
[11] 宋秀祖,许爱娥.皮肤屏障功能[J].国际皮肤性病学杂志,2007,33(2):122-124.
[12] 刘玮.皮肤屏障功能解析[C]//2012北京地区皮肤科学术年会论文集.北京:北京医学会,2012.
[13] Schäferkorting M,Bock U,Diembeck W,et al.The use of reconstructed human epidermis for skin absorption testing:Results of the validation study [J].Alternatives to Laboratory Animals Atla,2008,36(2):161-187.
[14] Incerti S,Mavon A,Moretto P.Reconstructed human epidermis:A model to study the barrier function [J].Nuclear Instruments & Methods in Physics Research,2005,231(1):286-291.
[15] Gabbanini S,Matera R,Beltramini C,et al.Analysis of in vitro release through reconstructed human epidermis and synthetic membranes of multi-vitamins from cosmetic formulations [J].Journal of Pharmaceutical & Biomedical Analysis,2010,52(4):461-467.
[16] Gabbanini S,Lucchi E,Carli M,et al.In vitro evaluation of the permea-tion through reconstructed human epidermis of essentials oils from cosmetic formulations [J].Journal of Pharmaceutical and Biomedical Analysis,2009,50(3):370-376.
[17] Rawlings A V,Harding C R.Moisturization and skin barrier function [J].Dermatologic Therapy,2004,17(S1):43-48.
[18] 程艳,祁彦,王超,等.保湿化妆品功效评价与发展展望[J].香料香精化妆品,2006(3):31-34.
[19] 张春晓,杜镇建,Wang Z,等.3D-人造皮肤模型在化妆品安全性、功效性评价中的应用[J].中国化妆品,2014(6):85-87.
[20] Frei V,Perrier E,Orly I,et al.Activation of fibroblast metabolism in a dermal and skin equivalent model:a screening test for activity of peptides [J].International Journal of Cosmetic Science,1998,20(3):159-173.
[21] Grazul-Bilska A T,Bilski J J,Redmer D A,et al.Antioxidant capacity of 3D human skin EpiDerm^TM model:effects of skin moisturizers [J].International Journal of Cosmetic Science,2009,31(3):201-208.
[22] Santamaría C,Revilla E,Miramontes E,et al.Protection against free radicals (UVB irradiation) of a water-soluble enzymatic extract from rice bran.Study using human keratinocyte monolayer and reconstructed human epidermis [J].Food & Chemical Toxicology,2010,48(1):83-88.
[23] Elias P M.The skin barrier as an innate immune element [J].Seminars in Immunopathology,2007,29(1):3-14.
[24] 侯伟,孙建方.敏感性皮肤[J].国际皮肤性病学杂志,2007,33(1):62-64.
[25] Ponec M,Kempenaar J.Use of human skin recombinants as an in vitro model for testing the irritation potential of cutaneous irritants [J].Skin Pharmacology,1995,8(1/2):49-59.
[26] Bernhofer L P,Seiberg M,Martin K M.The influence of the response of skin equivalent systems to topically applied consumer products by epithelial-mesenchymal interactions [J].Toxicology in Vitro,1999,13(2):219-229.
[27] Liang P P,Huang X Z,Yi J L,et al.A trichophyton rubrum infection model based on the reconstructed human epidermis - Episkin^®[J].Chinese Medical Journal,2016,129(1):54-58.
[28] Krutmann J,Liu W,Li L,et al.Pollution and skin:from epidemiological and mechanistic studies to clinical implications [J].Journal of Dermatological Science,2014,76(3):163-168.
[29] Boussouira B,Dang M P.Squalene and skin barrier function:From molecular target to biomarker of environmental exposure [M].West Berlin:Springer International Publishing,2016.
[30] Lecas S,Boursier E,Fitoussi R,et al.In vitro model adapted to the study of skin ageing induced by air pollution [J].Toxicology Letters,2016,259:60-68.
[31] Valacchi G,Muresan X M,Sticozzi C,et al.Ozone-induced damage in 3D-Skin Model is prevented by topical vitamin C and vitamin E compound mixtures application [J].Journal of Dermatological Science,2016,82(3):209-212.

Progress in field of research work for application of human-skin models in efficacy evaluation of cosmetics

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